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A quickly, effectively screening process of novel corona virus disease 2019 (COVID-19) in children in Shanghai, China

Identifieur interne : 000A24 ( 2020/Analysis ); précédent : 000A23; suivant : 000A25

A quickly, effectively screening process of novel corona virus disease 2019 (COVID-19) in children in Shanghai, China

Auteurs : Yu Shi [République populaire de Chine] ; Xiangshi Wang [République populaire de Chine] ; Gongbao Liu [République populaire de Chine] ; Qirong Zhu [République populaire de Chine] ; Jianshe Wang [République populaire de Chine] ; Hui Yu [République populaire de Chine] ; Chuanqing Wang [République populaire de Chine] ; Libo Wang [République populaire de Chine] ; Mingzhi Zhang [République populaire de Chine] ; Lingen Zhang [République populaire de Chine] ; Guoping Lu [République populaire de Chine] ; Zhujin Lu [République populaire de Chine] ; Jian Yu [République populaire de Chine] ; Zhongwei Qiao [République populaire de Chine] ; Ying Gu [République populaire de Chine] ; Guomei Shen [République populaire de Chine] ; Hong Xu [République populaire de Chine] ; Mei Zeng [République populaire de Chine] ; Xiaowen Zhai [République populaire de Chine] ; Guoying Huang [République populaire de Chine]

Source :

RBID : PMC:7154461

Abstract

Background

A recent cluster of pneumonia cases in China was caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We report the screening and diagnosis of corona virus disease 2019 (COVID-19) in our hospital.

Methods

Developed a procedure for the identification of children cases with COVID-19 in outpatient and emergency department of our hospital, then we observed how this process works.

Results

(I) There were 56 cases considered suspected cases, and 10 cases were confirmed as COVID-19. (II) Of the 10 confirmed COVID-19 cases admitted in our hospital, 5 were males and 5 were females, aged from 7 months to 11 years, the average age is 6.0±4.2 years, 6 cases were mild pneumonia, the others were upper respiratory tract infection. (III) We followed up 68 patients in isolation at home until symptoms disappeared. Non were missed in the patient’s first visit. The sensitivity of this method is 100% and the specificity is 71.3%.

Conclusions

Our screening process works well, and it is also necessary to establish a screening network in the hospital.


Url:
DOI: 10.21037/atm.2020.03.22
PubMed: NONE
PubMed Central: 7154461


Affiliations:


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PMC:7154461

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</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Zhang, Lingen" sort="Zhang, Lingen" uniqKey="Zhang L" first="Lingen" last="Zhang">Lingen Zhang</name>
<affiliation wicri:level="1">
<nlm:aff id="aff5">Department of Critical Care Medicine, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Lu, Guoping" sort="Lu, Guoping" uniqKey="Lu G" first="Guoping" last="Lu">Guoping Lu</name>
<affiliation wicri:level="1">
<nlm:aff id="aff5">Department of Critical Care Medicine, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Lu, Zhujin" sort="Lu, Zhujin" uniqKey="Lu Z" first="Zhujin" last="Lu">Zhujin Lu</name>
<affiliation wicri:level="1">
<nlm:aff id="aff5">Department of Critical Care Medicine, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Yu, Jian" sort="Yu, Jian" uniqKey="Yu J" first="Jian" last="Yu">Jian Yu</name>
<affiliation wicri:level="1">
<nlm:aff id="aff6">Department of Traditional Chinese Medicine, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Qiao, Zhongwei" sort="Qiao, Zhongwei" uniqKey="Qiao Z" first="Zhongwei" last="Qiao">Zhongwei Qiao</name>
<affiliation wicri:level="1">
<nlm:aff id="aff7">Department of Medical Image, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Gu, Ying" sort="Gu, Ying" uniqKey="Gu Y" first="Ying" last="Gu">Ying Gu</name>
<affiliation wicri:level="1">
<nlm:aff id="aff8">Department of Nursing, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Shen, Guomei" sort="Shen, Guomei" uniqKey="Shen G" first="Guomei" last="Shen">Guomei Shen</name>
<affiliation wicri:level="1">
<nlm:aff id="aff9">Outpatient and Emergency Management Office, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Xu, Hong" sort="Xu, Hong" uniqKey="Xu H" first="Hong" last="Xu">Hong Xu</name>
<affiliation wicri:level="1">
<nlm:aff id="aff10">Department of Nephrology/Rheumatology, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff11">Hospital Administration, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Zeng, Mei" sort="Zeng, Mei" uniqKey="Zeng M" first="Mei" last="Zeng">Mei Zeng</name>
<affiliation wicri:level="1">
<nlm:aff id="aff2">Department of Infectious Disease, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Zhai, Xiaowen" sort="Zhai, Xiaowen" uniqKey="Zhai X" first="Xiaowen" last="Zhai">Xiaowen Zhai</name>
<affiliation wicri:level="1">
<nlm:aff id="aff11">Hospital Administration, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff12">Department of Hematology/Oncology, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Huang, Guoying" sort="Huang, Guoying" uniqKey="Huang G" first="Guoying" last="Huang">Guoying Huang</name>
<affiliation wicri:level="1">
<nlm:aff id="aff11">Hospital Administration, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="aff13">Heart Center, National Children’s Medical Center,
<institution>Children’s Hospital of Fudan University</institution>
,
<addr-line>Shanghai 201102</addr-line>
,
<country>China</country>
</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Annals of Translational Medicine</title>
<idno type="ISSN">2305-5839</idno>
<idno type="eISSN">2305-5847</idno>
<imprint>
<date when="2020">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass></textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<sec>
<title>Background</title>
<p>A recent cluster of pneumonia cases in China was caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We report the screening and diagnosis of corona virus disease 2019 (COVID-19) in our hospital.</p>
</sec>
<sec>
<title>Methods</title>
<p>Developed a procedure for the identification of children cases with COVID-19 in outpatient and emergency department of our hospital, then we observed how this process works.</p>
</sec>
<sec>
<title>Results</title>
<p>(I) There were 56 cases considered suspected cases, and 10 cases were confirmed as COVID-19. (II) Of the 10 confirmed COVID-19 cases admitted in our hospital, 5 were males and 5 were females, aged from 7 months to 11 years, the average age is 6.0±4.2 years, 6 cases were mild pneumonia, the others were upper respiratory tract infection. (III) We followed up 68 patients in isolation at home until symptoms disappeared. Non were missed in the patient’s first visit. The sensitivity of this method is 100% and the specificity is 71.3%.</p>
</sec>
<sec>
<title>Conclusions</title>
<p>Our screening process works well, and it is also necessary to establish a screening network in the hospital.</p>
</sec>
</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>République populaire de Chine</li>
</country>
</list>
<tree>
<country name="République populaire de Chine">
<noRegion>
<name sortKey="Shi, Yu" sort="Shi, Yu" uniqKey="Shi Y" first="Yu" last="Shi">Yu Shi</name>
</noRegion>
<name sortKey="Gu, Ying" sort="Gu, Ying" uniqKey="Gu Y" first="Ying" last="Gu">Ying Gu</name>
<name sortKey="Huang, Guoying" sort="Huang, Guoying" uniqKey="Huang G" first="Guoying" last="Huang">Guoying Huang</name>
<name sortKey="Huang, Guoying" sort="Huang, Guoying" uniqKey="Huang G" first="Guoying" last="Huang">Guoying Huang</name>
<name sortKey="Liu, Gongbao" sort="Liu, Gongbao" uniqKey="Liu G" first="Gongbao" last="Liu">Gongbao Liu</name>
<name sortKey="Lu, Guoping" sort="Lu, Guoping" uniqKey="Lu G" first="Guoping" last="Lu">Guoping Lu</name>
<name sortKey="Lu, Zhujin" sort="Lu, Zhujin" uniqKey="Lu Z" first="Zhujin" last="Lu">Zhujin Lu</name>
<name sortKey="Qiao, Zhongwei" sort="Qiao, Zhongwei" uniqKey="Qiao Z" first="Zhongwei" last="Qiao">Zhongwei Qiao</name>
<name sortKey="Shen, Guomei" sort="Shen, Guomei" uniqKey="Shen G" first="Guomei" last="Shen">Guomei Shen</name>
<name sortKey="Wang, Chuanqing" sort="Wang, Chuanqing" uniqKey="Wang C" first="Chuanqing" last="Wang">Chuanqing Wang</name>
<name sortKey="Wang, Jianshe" sort="Wang, Jianshe" uniqKey="Wang J" first="Jianshe" last="Wang">Jianshe Wang</name>
<name sortKey="Wang, Libo" sort="Wang, Libo" uniqKey="Wang L" first="Libo" last="Wang">Libo Wang</name>
<name sortKey="Wang, Xiangshi" sort="Wang, Xiangshi" uniqKey="Wang X" first="Xiangshi" last="Wang">Xiangshi Wang</name>
<name sortKey="Xu, Hong" sort="Xu, Hong" uniqKey="Xu H" first="Hong" last="Xu">Hong Xu</name>
<name sortKey="Xu, Hong" sort="Xu, Hong" uniqKey="Xu H" first="Hong" last="Xu">Hong Xu</name>
<name sortKey="Yu, Hui" sort="Yu, Hui" uniqKey="Yu H" first="Hui" last="Yu">Hui Yu</name>
<name sortKey="Yu, Jian" sort="Yu, Jian" uniqKey="Yu J" first="Jian" last="Yu">Jian Yu</name>
<name sortKey="Zeng, Mei" sort="Zeng, Mei" uniqKey="Zeng M" first="Mei" last="Zeng">Mei Zeng</name>
<name sortKey="Zhai, Xiaowen" sort="Zhai, Xiaowen" uniqKey="Zhai X" first="Xiaowen" last="Zhai">Xiaowen Zhai</name>
<name sortKey="Zhai, Xiaowen" sort="Zhai, Xiaowen" uniqKey="Zhai X" first="Xiaowen" last="Zhai">Xiaowen Zhai</name>
<name sortKey="Zhang, Lingen" sort="Zhang, Lingen" uniqKey="Zhang L" first="Lingen" last="Zhang">Lingen Zhang</name>
<name sortKey="Zhang, Mingzhi" sort="Zhang, Mingzhi" uniqKey="Zhang M" first="Mingzhi" last="Zhang">Mingzhi Zhang</name>
<name sortKey="Zhu, Qirong" sort="Zhu, Qirong" uniqKey="Zhu Q" first="Qirong" last="Zhu">Qirong Zhu</name>
</country>
</tree>
</affiliations>
</record>

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